RESUMO
In recent years, the topic of vitamin D has been the subject of numerous publications covering a wide range of fields, with the corollary effect of overusing its routine dosage. However, substitution benefits only a small part of the population and systematic dosing of vitamin D outside risk situations is not recommended. This dosage of vitamin D is only useful if it results in effective treatment in case of deficiency. The purpose of this article is to provide a synthesis of current knowledge about vitamin D, in particular about the indications for its dosage in clinical practice.
Ces dernières années, le thème de la vitamine D a nourri de très nombreuses publications couvrant des domaines très variés avec comme effet corollaire une surutilisation de son dosage de routine. Toutefois, la substitution ne bénéficie qu'à une petite partie de la population et le dosage systématique de la vitamine D en dehors de situation à risque n'est pas recommandé. Ce dosage de la vitamine D n'a d'intérêt que s'il débouche sur un traitement efficace en cas de déficit. Le but de cet article est de proposer une synthèse des connaissances actuelles sur la vitamine D, en particulier au sujet des indications retenues pour son dosage en pratique clinique.
Assuntos
Deficiência de Vitamina D , Vitamina D , Vitaminas , Coleta de Dados , Suplementos Nutricionais , Humanos , Vitamina D/administração & dosagem , Deficiência de Vitamina D/tratamento farmacológicoRESUMO
OBJECTIVES/HYPOTHESIS: Evaluate the difference of the incidence in clinical Frey syndrome in studies comparing classical parotidectomy and parotidectomy with superficial musculoaponeurotic system (SMAS) flap elevation and suturing through meta-analysis methodology. STUDY DESIGN: Meta-analysis of controlled studies with and without SMAS flap. METHODS: Database search with the following key word combination: "Frey syndrome" and "SMAS." INCLUSION CRITERIA: parotidectomy, SMAS flap and control groups, minimal follow-up of 1 year. The outcome was the presence of clinical Frey syndrome. RESULTS: Eleven studies, mostly retrospective and not randomized. According to the fixed-effect model, SMAS technique is associated with a decrease of clinical Frey syndrome with an odds ratio (OR) of 0.42 (confidence interval [CI] 0.32-0.56). With the random-effect model, the difference remains significant (P = 0.006) with an OR of 0.25 (CI 0.09-0.66). The heterogeneity index I(2) is very high (85%). CONCLUSION: The use of SMAS flap and suturing is associated with a decreased incidence of Frey syndrome. Laryngoscope, 126:1581-1584, 2016.
